--- a/pixman/pixman-mmx.c
+++ b/pixman/pixman-mmx.c
@@ -89,7 +89,7 @@ _mm_mulhi_pu16 (__m64 __A, __m64 __B)
     return __A;
 }
 
-#  ifdef __OPTIMIZE__
+#  if defined(__OPTIMIZE__) && !defined(__clang__)
 extern __inline __m64 __attribute__((__gnu_inline__, __always_inline__, __artificial__))
 _mm_shuffle_pi16 (__m64 __A, int8_t const __N)
 {